In Vivo Targeting of Xenografted Human Cancer Cells with Functionalized Fluorescent Silica Nanoparticles in Zebrafish
4.6K Views
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10:26 min
•
May 8th, 2020
DOI :
May 8th, 2020
•Xiaodan Qin*1, Fabrice F. J. Laroche*1, Saquib Ahmed M. A. Peerzade2, Andrew Lam1, Igor Sokolov2,3,4, Hui Feng1
1Departments of Pharmacology and Medicine, Section of Hematology and Medical Oncology, The Cancer Research Center, Boston University School of Medicine, 2Department of Biomedical Engineering, Tufts University, 3Department of Mechanical Engineering, Tufts University, 4Department of Physics, Tufts University
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Chapters in this video
0:04
Introduction
0:54
Generation of Casper Zebrafish Embryos
2:33
Preparing Materials for Cancer Cell Transplantation
3:34
Preparing Cancer Cells for Transplantation
5:20
Transplantation of Cancer Cells
6:54
Injection of Nanoparticles or Vehicle
7:40
Imaging and Tracking of Nanoparticles and Cancer Cells
8:45
Results: Colocalization of Cancer Cells and Nanoparticles
9:47
Conclusion
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