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Core - Molecular Biology

    Chapter 3

    Protein Structure

    3.1 : What are Proteins?

    3.1 : What are Proteins?

    Overview Proteins are chains of amino acids that are connected by peptide bonds and folded into a 3-dimensional structure. The side chains of individual ...

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    3.2 : Protein Organization

    3.2 : Protein Organization

    Overview Proteins are one of the fundamental building blocks of life that carry out many diverse functions in the cell. Proteins are assembled from amino ...

    20.0K views
    3.3 : Protein Folding

    3.3 : Protein Folding

    Overview Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation which ...

    31.6K views
    3.4 : Conservation of Protein Domains Over Different Proteins02:26

    3.4 : Conservation of Protein Domains Over Different Proteins

    Protein domains are small structurally independent units that are part of a single amino acid chain.  Although these domains are often structurally ...

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    3.5 : Globular and Fibrous Proteins02:21

    3.5 : Globular and Fibrous Proteins

    Many proteins can be classified into two distinct subtypes - globular or fibrous. These two types differ in their shapes and solubilities. Globular ...

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    3.6 : Intrinsically Disordered Proteins02:18

    3.6 : Intrinsically Disordered Proteins

    Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows ...

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    3.7 : Protein Complex Assembly02:41

    3.7 : Protein Complex Assembly

    Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes ...

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    3.8 : Conjugated Proteins02:50

    3.8 : Conjugated Proteins

    Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with ...

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    3.9 : Amyloid Fibrils03:03

    3.9 : Amyloid Fibrils

    Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or ...

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    3.10 : Antibody Structure

    3.10 : Antibody Structure

    Overview Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced ...

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    3.11 : Protein Families02:47

    3.11 : Protein Families

    Protein families are groups of homologous proteins; that is, they have similarities in amino acid sequences and three-dimensional structures. Protein ...

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