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Core - Molecular Biology

Chapter 3

Protein Structure

3.1 : What are Proteins?

3.1 : What are Proteins?

Overview Proteins are chains of amino acids that are connected by peptide bonds and folded into a 3-dimensional structure. The side chains of individual ...

3.2 : Protein Organization

3.2 : Protein Organization

Overview Proteins are one of the fundamental building blocks of life that carry out many diverse functions in the cell. Proteins are assembled from amino ...

3.3 : Protein Folding

3.3 : Protein Folding

Overview Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation which ...

3.4 : Conservation of Protein Domains Over Different Proteins

3.4 : Conservation of Protein Domains Over Different Proteins

Protein domains are small structurally independent units that are part of a single amino acid chain. Although these domains are often structurally ...

3.5 : Globular and Fibrous Proteins

3.5 : Globular and Fibrous Proteins

Many proteins can be classified into two distinct subtypes - globular or fibrous. These two types differ in their shapes and solubilities. Globular ...

3.6 : Intrinsically Disordered Proteins

3.6 : Intrinsically Disordered Proteins

Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows ...

3.7 : Protein Complex Assembly

3.7 : Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types. Most protein complexes ...

3.8 : Conjugated Proteins

3.8 : Conjugated Proteins

Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with ...

3.9 : Amyloid Fibrils

3.9 : Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins. Under most circumstances, misfolded proteins are either refolded by chaperone proteins or ...

3.10 : Antibody Structure

3.10 : Antibody Structure

Overview Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced ...

3.11 : Protein Families

3.11 : Protein Families

Protein families are groups of homologous proteins; that is, they have similarities in amino acid sequences and three-dimensional structures. Protein ...

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