Generation of Alpha-Synuclein Preformed Fibrils from Monomers and Use In Vivo
Please note that all translations are automatically generated. Click here for the English version.
21.2K Views
•
09:44 min
•
June 2nd, 2019
DOI :
June 2nd, 2019
•Joseph R. Patterson1, Nicole K. Polinski2, Megan F. Duffy1,3, Christopher J. Kemp1, Kelvin C. Luk4, Laura A. Volpicelli-Daley5, Nicholas M. Kanaan1, Caryl E. Sortwell1,3,6
1Department of Translational Science and Molecular Medicine, Michigan State University, 2The Michael J. Fox Foundation for Parkinson's Research, 3Neuroscience Program, Michigan State University, 4Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, 5Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, 6Mercy Health Hauenstein Neuroscience Medical Center
Przeglądaj więcej filmów
Rozdziały w tym wideo
0:04
Title
1:13
Formation of α-synuclein Preformed Fibrils from Monomers
2:20
Sonication of α-synuclein Preformed Fibrils
4:37
Preparation of Custom Glass Needle Syringes for Stereotactic Injections
7:18
Results: Analysis of the Generated Alpha-Synuclein Preformed Fibrils
9:22
Conclusion
Powiązane Filmy
12:01
Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein
10.7K Views
09:27
Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains
17.2K Views
09:32
Bioluminescence Imaging of Neuroinflammation in Transgenic Mice After Peripheral Inoculation of Alpha-Synuclein Fibrils
8.5K Views
09:16
Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation
7.5K Views
05:48
Rapid Generation of Amyloid from Native Proteins In vitro
6.1K Views
10:03
Studying Pre-formed Fibril Induced α-Synuclein Accumulation in Primary Embryonic Mouse Midbrain Dopamine Neurons
10.5K Views
Stereotaxic Intracranial Delivery of Chemicals, Proteins or Viral Vectors to Study Parkinson's Disease
3.6K Views
04:49
Technique for Intranasal Administration of α-Synuclein Aggregates
358 Views
08:24
A Method to Study α-Synuclein Toxicity and Aggregation Using a Humanized Yeast Model
2.1K Views
01:19
Indukcja zapalenia nerwów u myszy poprzez wstrzyknięcie włókien alfa-synukleiny
30 Views
Copyright © 2025 MyJoVE Corporation. Wszelkie prawa zastrzeżone