Generation of Human Brain Organoids for Mitochondrial Disease Modeling
6.0K Views
•
08:09 min
•
June 21st, 2021
DOI :
June 21st, 2021
•Stephanie Le1, Laura Petersilie2, Gizem Inak1,4, Carmen Menacho-Pando1, Karl W. Kafitz2, Agnieszka Rybak-Wolf3, Nikolaus Rajewsky3, Christine R. Rose2, Alessandro Prigione1,5
1Department of General Pediatrics, Neonatology and Pediatric Cardiology, Duesseldorf University Hospital, Medical Faculty, Heinrich Heine University, 2Institute of Neurobiology, Heinrich Heine University, 3Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrueck Center for Molecular Medicine (MDC), 4Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, 5Max Delbrueck Center for Molecular Medicine (MDC)
Chapters in this video
0:05
Introduction
0:44
Generation of Brain Organoids
5:31
Immunostaining of Brain Organoids
6:07
Results: Visualization and Bioenergetic Profiling of Brain Organoids Generated from iPSCs
7:34
Conclusion
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