Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples
7.6K Views
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08:54 min
•
May 19th, 2020
DOI :
May 19th, 2020
•Andrew Reckers1, Anita Wen1, David Aguilar1, Peter Bacchetti2, Monica Gandhi3, John Metcalfe4, Roy Gerona1
1Department of Obstetrics, Gynecology and Reproductive Sciences, TB Hair Analysis Laboratory, University of California San Francisco, 2Department of Epidemiology and Biostatistics, University of California San Francisco, 3Department of Medicine, Division of HIV, Infectious Diseases, and Global Medicine, University of California San Francisco, 4Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California San Francisco
Chapters in this video
0:04
Introduction
1:20
Hair Sampling
2:32
Drug Extraction
4:18
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) Preparation
5:35
Data Analysis
6:47
Results: Representative Drug-Resistant (DR) TB Medication Quantification
7:55
Conclusion
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