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Generation of Induced Neural Stem Cells from Peripheral Mononuclear Cells and Differentiation Toward Dopaminergic Neuron Precursors for Transplantation Studies

7.1K Views

12:13 min

July 11th, 2019

DOI :

10.3791/59690-v

July 11th, 2019


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Induced Neural Stem Cells

Chapters in this video

0:04

Title

1:31

Isolation of PBMNCs (Peripheral Blood Mononuclear Cells)

3:00

Expansion of MNCs

4:12

Reprogramming of PBMNCs to iNSCs (Induced Neural Stem Cells) by SeV (Sendai Virus) Infection

7:20

Establishment of Unilateral 6-Hyroxydopamine (6-OHDA)-Lesioned Parkinson s Disease (PD) Mouse Models

9:15

Results: Induced Neural Stem Cells Differentiation Toward Dopaminergic Neuron Precursors and Treatment of Parkinson s Disease Mouse Models

11:00

Conclusion

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