In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis
17.7K Views
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07:25 min
•
May 4th, 2017
DOI :
May 4th, 2017
•Nohemi Salinas-Jazmín1,2, Edith González-González1, Luz X. Vásquez-Bochm3, Sonia M. Pérez-Tapia4,5, Marco A. Velasco-Velázquez6
1Unit for Development and Research in Bioprocesses Unit (UDIBI), National School of Biological Sciences, National Polytechnic Institute (IPN), University of Mexico (UNAM), 2School of Chemistry, National Autonomous University of Mexico (UNAM), 3Graduate Program in Chemical Sciences, National Autonomous University of Mexico (UNAM), 4Unit for Development Research and Medical Innovation in Biotechnology (UDIMEB), National School of Biological Sciences, National Polytechnic Institute (IPN), 5Department of Immunology, National Scool of Biological Sciences, National Polytechnic Institute (IPN), 6Department of Pharmacology and Unit of Translational Biomedicine (CMN 20 de noviembre), School of Medicine, National Autonomous University of Mexico (UNAM)
Chapters in this video
0:05
Title
0:48
Flow Cytometric Target Binding Analysis
3:35
Complement-dependent Cytotoxicity (CDC) Assessment
5:29
Results: Representative Anti-CD20 Therapeutic Monoclonal Antibody Analyses
6:38
Conclusion
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