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Core - Cell Biology

    Chapter 41

    Fibroblast Transformation and Muscle Stem Cells

    41.1 : Connective Tissue Cell Types01:22

    41.1 : Connective Tissue Cell Types

    Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing ...

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    41.2 : Introduction to Fibroblasts01:09

    41.2 : Introduction to Fibroblasts

    Rudolph Virchow discovered spindle-shaped cells called fibroblasts in 1858. Inactive fibroblasts, called fibrocytes, become activated by various stimuli, ...

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    41.3 : Mesenchymal Stem Cells01:19

    41.3 : Mesenchymal Stem Cells

    Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, ...

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    41.4 : Growth of Cartilage and Bone Tissue01:27

    41.4 : Growth of Cartilage and Bone Tissue

    Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo ...

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    41.5 : Osteoclasts in Bone Remodeling01:31

    41.5 : Osteoclasts in Bone Remodeling

    Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. ...

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    41.6 : Overview of Skeletal Muscle01:15

    41.6 : Overview of Skeletal Muscle

    Skeletal muscles are composed of a bundle of muscle fibers and are attached to bones through tendons. Each skeletal muscle fiber is a single muscle cell. ...

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    41.7 : Formation of Muscle Fibers from Myoblasts01:13

    41.7 : Formation of Muscle Fibers from Myoblasts

    De novo myogenesis, or the formation of muscle fibers, begins during the early embryonic stages. The skeletal muscle is formed from somites– blocks ...

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    41.8 : Satellite Stem Cells and Muscular Dystrophy01:21

    41.8 : Satellite Stem Cells and Muscular Dystrophy

    Satellite stem cells or myosatellite cells are quiescent stem cells that Alexander Mauro first identified in 1961. These cells are located between the ...

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