Michael J. Iadarola

Protein kinase C(alpha) is required for vanilloid receptor 1 activation. Evidence for multiple signaling pathways.

Reproducibility of pain measurement and pain perception.

Cystatin C as a cerebrospinal fluid biomarker for pain in humans.

Direct interstitial infusion of NK1-targeted neurotoxin into the spinal cord: a computational model.

Peripherally induced resiniferatoxin analgesia.

Resiniferatoxin-induced loss of plasma membrane in vanilloid receptor expressing cells.

Vanilloid receptor 1 regulates multiple calcium compartments and contributes to Ca2+-induced Ca2+ release in sensory neurons.

Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control.

Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament.

Comparison of experimental and acute clinical pain responses in humans as pain phenotypes.

Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling.

Peripheral targeting of the trigeminal ganglion via the infraorbital foramen as a therapeutic strategy.

Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation.

Physiologic and antinociceptive effects of intrathecal resiniferatoxin in a canine bone cancer model.

Cyclin-dependent kinase 5 activity regulates pain signaling.

Modulatory roles of the NPFF system in pain mechanisms at the spinal level.

Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1.

Modulatory role of neuropeptide FF system in nociception and opiate analgesia.

Peripheral inflammation increases Scya2 expression in sensory ganglia and cytokine and endothelial related gene expression in inflamed tissue.

Complete pain relief: potential problems and diagnostic solutions.

High definition profiling of autoantibodies to glutamic acid decarboxylases GAD65/GAD67 in stiff-person syndrome.

Localization of S100A8 and S100A9 expressing neutrophils to spinal cord during peripheral tissue inflammation.

Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia.

Rapid, novel, specific, high-throughput assay for diagnosis of Loa loa infection.

A new luminescence assay for autoantibodies to mammalian cell-prepared insulinoma-associated protein 2.

A luciferase immunoprecipitation systems assay enhances the sensitivity and specificity of diagnosis of Strongyloides stercoralis infection.

Structure-activity relationships of 1,4-dihydropyridines that act as enhancers of the vanilloid receptor 1 (TRPV1).

Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP).

Tumor necrosis factor-alpha regulates cyclin-dependent kinase 5 activity during pain signaling through transcriptional activation of p35.

Serological diagnosis of human herpes simplex virus type 1 and 2 infections by luciferase immunoprecipitation system assay.

Four-antigen mixture containing v-cyclin for serological screening of human herpesvirus 8 infection.

Highly quantitative serological detection of anti-cytomegalovirus (CMV) antibodies.

A four-antigen mixture for rapid assessment of Onchocerca volvulus infection.

Sensitive and robust luminescent profiling of anti-La and other autoantibodies in Sjogren's syndrome.

Cytokine gene expression after total hip arthroplasty: surgical site versus circulating neutrophil response.

Rapid serological detection of autoantibodies associated with Sjögren's syndrome.

Comparison of radioimmunoprecipitation with luciferase immunoprecipitation for autoantibodies to GAD65 and IA-2beta.

High levels of Anti-GAD65 and Anti-Ro52 autoantibodies in a patient with major depressive disorder showing psychomotor disturbance.

RT-PCR analysis of pain genes: use of gel-based RT-PCR for studying induced and tissue-enriched gene expression.

Rapid, simple, quantitative, and highly sensitive antibody detection for lyme disease.

Prolonged analgesic response of cornea to topical resiniferatoxin, a potent TRPV1 agonist.

Extraordinary antigenicity of the human Ro52 autoantigen.

Distinct profiles of antibodies to Kaposi sarcoma-associated herpesvirus antigens in patients with Kaposi sarcoma, multicentric Castleman disease, and primary effusion lymphoma.

Antibody-profiling technologies for studying humoral responses to infectious agents.

Proteome-wide anti-hepatitis C virus (HCV) and anti-HIV antibody profiling for predicting and monitoring the response to HCV therapy in HIV-coinfected patients.

Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia.

Synthetic biology for translational research.

Rapid induction of autoantibodies during ARDS and septic shock.

Ablation of rat TRPV1-expressing Adelta/C-fibers with resiniferatoxin: analysis of withdrawal behaviors, recovery of function and molecular correlates.

Recombinant expression of the AChR-alpha1 subunit for the detection of conformation-dependent epitopes in Myasthenia Gravis.

LIPS arrays for simultaneous detection of antibodies against partial and whole proteomes of HCV, HIV and EBV.

Emerging tactical strategies for fighting the war on cancer based on the genetic landscape.

The vanilloid agonist resiniferatoxin for interventional-based pain control.

Searching for biomarkers: humoral response profiling with luciferase immunoprecipitation systems.

Resveratrol inhibits Cdk5 activity through regulation of p35 expression.

Antibody profiling of Borrelia burgdorferi infection in horses.

Microfluidic LIPS for serum antibody detection: demonstration of a rapid test for HSV-2 infection.

Serological studies confirm the novel astrovirus HMOAstV-C as a highly prevalent human infectious agent.

Small molecule positive allosteric modulation of TRPV1 activation by vanilloids and acidic pH.