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A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors

14.8K Views

12:40 min

December 7th, 2014

DOI :

10.3791/51984-v

December 7th, 2014


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Keywords BCR ABL

Rozdziały w tym wideo

0:05

Title

1:33

Preparation of Random Mutation Library by Random Mutagenisis

3:38

Production of Retroviral Supernatants

5:13

Selection of Resistant Clones In Vitro

8:15

In Vitro Validation of Resistant Mutations

9:58

Results: Identification and Validation of Ruxolitinib Resistant Mutations

12:04

Concluion

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