Department of Biomedical Engineering,
Johns Hopkins Translational ImmunoEngineering Center,
Department of Dermatology,
Department of Oncology,
Department of Pathology
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The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures.
Biomaterials Nov, 2010 | Pubmed ID: 20674001
Drug delivery strategies for therapeutic angiogenesis and antiangiogenesis.
Expert opinion on drug delivery Apr, 2011 | Pubmed ID: 21338327
Non-viral gene delivery nanoparticles based on poly(β-amino esters) for treatment of glioblastoma.
Biomaterials Aug, 2011 | Pubmed ID: 21536325
Effects of base polymer hydrophobicity and end-group modification on polymeric gene delivery.
Biomacromolecules Oct, 2011 | Pubmed ID: 21888340
Gene delivery nanoparticles specific for human microvasculature and macrovasculature.
Nanomedicine : nanotechnology, biology, and medicine Oct, 2012 | Pubmed ID: 22306159
Poly(β-amino ester)-nanoparticle mediated transfection of retinal pigment epithelial cells in vitro and in vivo.
PloS one , 2012 | Pubmed ID: 22629417
Advances in polymeric and inorganic vectors for nonviral nucleic acid delivery.
Therapeutic delivery Apr, 2011 | Pubmed ID: 22826857
Uptake and transfection with polymeric nanoparticles are dependent on polymer end-group structure, but largely independent of nanoparticle physical and chemical properties.
Molecular pharmaceutics Nov, 2012 | Pubmed ID: 22970908
The effect and role of carbon atoms in poly(β-amino ester)s for DNA binding and gene delivery.
Journal of the American Chemical Society May, 2013 | Pubmed ID: 23570657
Nanoengineering approaches to the design of artificial antigen-presenting cells.
Nanomedicine (London, England) Jul, 2013 | Pubmed ID: 23837856
Particle shape dependence of CD8+ T cell activation by artificial antigen presenting cells.
Biomaterials Jan, 2014 | Pubmed ID: 24099710
Differential polymer structure tunes mechanism of cellular uptake and transfection routes of poly(β-amino ester) polyplexes in human breast cancer cells.
Bioconjugate chemistry Jan, 2014 | Pubmed ID: 24320687
PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma.
The New England journal of medicine Jun, 2016 | Pubmed ID: 27093365
PD-L1 Expression in Melanoma: A Quantitative Immunohistochemical Antibody Comparison.
Clinical cancer research : an official journal of the American Association for Cancer Research Aug, 2017 | Pubmed ID: 28428193
Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy.
Nanomedicine : nanotechnology, biology, and medicine 02, 2018 | Pubmed ID: 29127039
Anisotropic biodegradable lipid coated particles for spatially dynamic protein presentation.
Acta biomaterialia May, 2018 | Pubmed ID: 29631048
Multidimensional, quantitative assessment of PD-1/PD-L1 expression in patients with Merkel cell carcinoma and association with response to pembrolizumab.
Journal for immunotherapy of cancer Oct, 2018 | Pubmed ID: 30285852
High-throughput evaluation of polymeric nanoparticles for tissue-targeted gene expression using barcoded plasmid DNA.
Journal of controlled release : official journal of the Controlled Release Society Sep, 2021 | Pubmed ID: 34097924
Analysis of multispectral imaging with the AstroPath platform informs efficacy of PD-1 blockade.
Science (New York, N.Y.) Jun, 2021 | Pubmed ID: 34112666
Immune cell subsets in interface cutaneous immune-related adverse events associated with anti-PD-1 therapy resemble acute graft versus host disease more than lichen planus.
Journal of cutaneous pathology Aug, 2022 | Pubmed ID: 35445765
Disseminated Tuberculosis With an Atypical Cutaneous Manifestation in a Hematopoietic Cell Transplant Patient in the Early Posttransplant Period: Case Report and Review of the Literature.
Open forum infectious diseases Dec, 2022 | Pubmed ID: 36570971
IFNα and 5-Aza-2'-deoxycytidine combined with a dendritic-cell targeting DNA vaccine alter tumor immune cell infiltration in the B16F10 melanoma model.
Frontiers in immunology , 2022 | Pubmed ID: 36741387
Whole-Slide Imaging, Mutual Information Registration for Multiplex Immunohistochemistry and Immunofluorescence.
Laboratory investigation; a journal of technical methods and pathology Aug, 2023 | Pubmed ID: 37196983
Pembrolizumab-Induced Lichen Planus Pemphigoides in a Patient with Metastatic Adrenocortical Cancer: A Case Report and Literature Review.
Dermatopathology (Basel, Switzerland) Aug, 2023 | Pubmed ID: 37606485
Biomaterial-Mediated Genetic Reprogramming of Merkel Cell Carcinoma and Melanoma Leads to Targeted Cancer Cell Killing and .
ACS biomaterials science & engineering Nov, 2023 | Pubmed ID: 37797944
qMAP enabled microanatomical mapping of human skin aging.
bioRxiv : the preprint server for biology Jul, 2024 | Pubmed ID: 39005293
Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy.
Cell Oct, 2024 | Pubmed ID: 39243764
Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma.
Nature immunology Nov, 2024 | Pubmed ID: 39455893
Concordance of Whole-Slide Imaging and Conventional Light Microscopy for Assessment of Pathologic Response Following Neoadjuvant Therapy for Lung Cancer.
Laboratory investigation; a journal of technical methods and pathology Jan, 2025 | Pubmed ID: 39461426
Highly Multiplexed Immunofluorescence PhenoCycler Panel for Murine Formalin-Fixed Paraffin-Embedded Tissues Yields Insight Into Tumor Microenvironment Immunoengineering.
Laboratory investigation; a journal of technical methods and pathology Jan, 2025 | Pubmed ID: 39490742
Lymphocyte Activation Gene 3 Expression, γδ T-Cell/Major Histocompatibility Complex Class I Interactions, and Prognosis in Merkel Cell Carcinoma.
Laboratory investigation; a journal of technical methods and pathology Jan, 2025 | Pubmed ID: 39510251
Three-Dimensional Nuclear Architecture and Genomic Structural Variations in Melanoma.
The Journal of investigative dermatology Jun, 2025 | Pubmed ID: 39725157
Society for Immunotherapy of Cancer: updates and best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) image analysis and data sharing.
Journal for immunotherapy of cancer Jan, 2025 | Pubmed ID: 39779210
Clinical and histopathological characterization of enfortumab vedotin-associated cutaneous toxicities: A case series.
JAAD case reports Mar, 2025 | Pubmed ID: 40124881
The role of USMLE Step 2 scores in the dermatology match process: a comparative analysis between Charting the Outcomes and Texas STAR.
Archives of dermatological research Apr, 2025 | Pubmed ID: 40299048
Racial disparities in the diagnosis and treatment of dermatofibrosarcoma protuberans.
Journal of the American Academy of Dermatology May, 2025 | Pubmed ID: 40339807
Sachin S. Surwase*,1,2,3,
Xin Ming M. Zhou*,3,4,
Kathryn M. Luly1,2,3,
Qingfeng Zhu5,6,7,
Niki Talebian6,
Robert A. Anders5,6,7,8,9,
Jordan J. Green1,2,3,5,8,9,10,11,12,
Stephany Y. Tzeng1,2,3,
Joel C. Sunshine1,3,4,5,6,8,9
1Department of Biomedical Engineering, Johns Hopkins University,
2Translational Tissue Engineering Center, Johns Hopkins University,
3Johns Hopkins Translational ImmunoEngineering Center, Johns Hopkins University,
4Department of Dermatology, Johns Hopkins University,
5Department of Oncology, Johns Hopkins University,
6Department of Pathology, Johns Hopkins University,
7Convergence Institute, Sidney Kimmel Comprehensive Cancer Center Johns Hopkins University School of Medicine,
8Bloomberg Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine,
9Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine,
10Institute for Nanobiotechnology, Johns Hopkins University,
11Departments of Neurosurgery and Ophthalmology, Johns Hopkins University School of Medicine,
12Departments of Materials Science & Engineering and Chemical & Biomolecular Engineering, Johns Hopkins University
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