Department of Biomedical Engineering
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Structural and optical characterization of Zn(OH)2 and its composites with graphite oxides.
Optics letters Mar, 2013 | Pubmed ID: 23503274
Time-resolved photoluminescence of Zn(OH)2 and its composites with graphite oxides.
Optics letters Jul, 2013 | Pubmed ID: 23811885
Quantification of blood-brain barrier solute permeability and brain transport by multiphoton microscopy.
Journal of biomechanical engineering Mar, 2014 | Pubmed ID: 24193698
Optical biopsy identification and grading of gliomas using label-free visible resonance Raman spectroscopy.
Journal of biomedical optics 09, 2019 | Pubmed ID: 31512439
Mid-infrared metabolic imaging with vibrational probes.
Nature methods 08, 2020 | Pubmed ID: 32601425
Mammalian cell and tissue imaging using Raman and coherent Raman microscopy.
Wiley interdisciplinary reviews. Systems biology and medicine Nov, 2020 | Pubmed ID: 32686297
Enhanced stimulated raman scattering of solvent due to anharmonic energy transfer from resonance raman solute molecules.
Optics express Jul, 2020 | Pubmed ID: 32752451
Advances in stimulated Raman scattering imaging for tissues and animals.
Quantitative imaging in medicine and surgery Mar, 2021 | Pubmed ID: 33654679
Distinct Cellular Profiles of and mRNA Localization in Microglia, Astrocytes and Neurons during a Period of Vascular Maturation in the Auditory Brainstem of Neonate Rats.
Brain sciences Jul, 2021 | Pubmed ID: 34356178
Highly-multiplexed volumetric mapping with Raman dye imaging and tissue clearing.
Nature biotechnology Mar, 2022 | Pubmed ID: 34608326
DO-SRS imaging of metabolic dynamics in aging .
The Analyst Dec, 2021 | Pubmed ID: 34781326
Visualizing Cancer Cell Metabolic Dynamics Regulated With Aromatic Amino Acids Using DO-SRS and 2PEF Microscopy.
Frontiers in molecular biosciences , 2021 | Pubmed ID: 34977157
A high-throughput technique to map cell images to cell positions using a 3D imaging flow cytometer.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2022 | Pubmed ID: 35173045
DO-SRS imaging of diet regulated metabolic activities in Drosophila during aging processes.
Aging cell Apr, 2022 | Pubmed ID: 35257470
Imaging Sub-Cellular Methionine and Insulin Interplay in Triple Negative Breast Cancer Lipid Droplet Metabolism.
Frontiers in oncology , 2022 | Pubmed ID: 35359364
Direct Imaging of Lipid Metabolic Changes in Ovary During Aging Using DO-SRS Microscopy.
Frontiers in aging , 2021 | Pubmed ID: 35822015
Fano resonance line shapes in the Raman spectra of tubulin and microtubules reveal quantum effects.
Biophysical reports Mar, 2022 | Pubmed ID: 36425084
Alzheimer's-Associated Upregulation of Mitochondria-Associated ER Membranes After Traumatic Brain Injury.
Cellular and molecular neurobiology Dec, 2022 | Pubmed ID: 36571634
Super-resolution SRS microscopy with A-PoD.
Nature methods Mar, 2023 | Pubmed ID: 36797410
Femtosecond Optical Kerr Gates in Cancerous Breast Tissue for a New Optical Biopsy Method.
Research square May, 2023 | Pubmed ID: 37214848
Bioorthogonal Stimulated Raman Scattering Imaging Uncovers Lipid Metabolic Dynamics in Brain During Aging.
GEN biotechnology Jun, 2023 | Pubmed ID: 37363411
Goldilocks Energy Minimum: Peptide-Based Reversible Aggregation and Biosensing.
ACS applied materials & interfaces Sep, 2023 | Pubmed ID: 37651748
Early cancer detection by SERS spectroscopy and machine learning.
Light, science & applications Sep, 2023 | Pubmed ID: 37714845
Self-Assembled Homopolymeric Spherulites from Small Molecules in Solution.
Journal of the American Chemical Society Nov, 2023 | Pubmed ID: 37921495
Femtosecond optical Kerr effect in normal and grades of cancerous breast tissues as a new optical biopsy method.
Journal of biophotonics Feb, 2024 | Pubmed ID: 38010367
Multimodal imaging of metabolic activities for distinguishing subtypes of breast cancer.
Biomedical optics express Nov, 2023 | Pubmed ID: 38021123
Super-Resolution Stimulated Raman Scattering Microscopy with Graphical User Interface-Supported A-PoD.
Current protocols Jan, 2024 | Pubmed ID: 38270527
Multi-molecular hyperspectral PRM-SRS microscopy.
Nature communications Feb, 2024 | Pubmed ID: 38383552
Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK.
Cell metabolism Jun, 2024 | Pubmed ID: 38657612
Virtual-point-based deconvolution for optical-resolution photoacoustic microscopy.
Journal of biophotonics Aug, 2024 | Pubmed ID: 38934081
Label-Free Optical Biopsy Reveals Biomolecular and Morphological Features of Diabetic Kidney Tissue in 2D and 3D.
bioRxiv : the preprint server for biology Oct, 2024 | Pubmed ID: 39553929
Metabolic nanoscopy enhanced by experimental and computational approaches.
Npj imaging , 2024 | Pubmed ID: 39677560
Multimodal Imaging Unveils the Impact of Nanotopography on Cellular Metabolic Activities.
Chemical & biomedical imaging Dec, 2024 | Pubmed ID: 39735831
Innovations in aging biology: highlights from the ARDD emerging science & technologies workshop.
npj aging Feb, 2025 | Pubmed ID: 39966395
Cancer Cell Line Classification Using Raman Spectroscopy of Cancer-Derived Exosomes and Machine Learning.
Analytical chemistry Apr, 2025 | Pubmed ID: 40145503
Single-Frame Vignetting Correction for Post-Stitched-Tile Imaging Using VISTAmap.
Nanomaterials (Basel, Switzerland) Apr, 2025 | Pubmed ID: 40214608
Illuminating life processes by vibrational probes.
Nature methods May, 2025 | Pubmed ID: 40360917
Label-free multimodal optical biopsy reveals biomolecular and morphological features of diabetic kidney tissue in 2D and 3D.
Nature communications May, 2025 | Pubmed ID: 40374604
Optical imaging of metabolic dynamics in ALS under methionine regulation.
Journal of biomedical optics Feb, 2025 | Pubmed ID: 40417702
1Shu Chien-Gene Lay Department of Bioengineering, University of California San Diego,
2Aiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California San Diego,
3Department of Electrical and Computer Engineering, University of California San Diego,
4Institute of Engineering in Medicine, University of California San Diego,
5Synthetic Biology Institute, University of California San Diego
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