Chapter 23
Drugs for Chronic Bowel Disorders
慢性腸疾患: はじめに
Chronic bowel disorders are long-term medical conditions affecting the digestive tract, including disorders such as irritable bowel syndrome or IBS and ...
下痢型過敏性腸症候群の治療薬
Diarrhea-predominant irritable bowel syndrome or IBS-D, is characterized by chronic abdominal pain and diarrhea.
Effective IBS-D management involves ...
便秘型過敏性腸症候群（IBS-C）の治療薬
Irritable bowel syndrome with constipation or IBS-C, is a recurring digestive disorder characterized by abdominal pain and infrequent bowel movements.
...
IBD における潰瘍性大腸炎の治療薬
Ulcerative colitis is characterized by mucosal inflammation of the colon.
The first-line agent, 5-aminosalicylic acid or 5-ASA, inhibits leukotriene and ...
免疫調節薬を用いた IBD におけるクローン病の治療薬
Crohn's disease is an inflammatory bowel disorder characterized by discontinuous chronic inflammation of the GI tract.
Treatment strategies encompass ...
生物学的製剤を用いた炎症性腸疾患におけるクローン病の治療薬：抗TNF
Tumor necrosis factor, or TNF, a proinflammatory cytokine, exists in soluble or membrane-bound form.
TNF-receptor interaction triggers NF-κB, T-cell ...
グルココルチコイドを使用した炎症性腸疾患におけるクローン病の治療薬
Glucocorticoids, like prednisone, are potent anti-inflammatory agents that induce effective remission in Crohn's patients.
These bind and activate ...
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