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Chapter 17

Pharmacotherapy of the Epilepsies

てんかんと発作: 概要
てんかんと発作: 概要
Epilepsy is a chronic neurological disorder characterized by recurrent, unpredictable seizures. Seizures result from abnormal electrical discharges in the ...
発作: 分類
発作: 分類
Epilepsy is a chronic neurological disorder characterized by unpredictable seizures. Seizures can be provoked by identifiable factors or occur ...
抗てんかん薬:ナトリウムチャネル遮断薬
抗てんかん薬:ナトリウムチャネル遮断薬
Antiepileptic drugs, essential in managing epilepsy, effectively prevent seizures by blocking the movement of sodium ions through channels in the ...
抗てんかん薬:GABA 経路増強剤
抗てんかん薬:GABA 経路増強剤
γ-aminobutyric acid or GABA pathway potentiators are drugs used to manage epilepsy by enhancing GABA neurotransmission, a critical inhibitory pathway ...
抗てんかん薬:カルシウムチャネル遮断薬
抗てんかん薬:カルシウムチャネル遮断薬
Calcium channel blockers, primarily known for cardiovascular use, have also shown potential as antiepileptic drugs. They exert their effects by modulating ...
抗てんかん薬:グルタミン酸拮抗薬
抗てんかん薬:グルタミン酸拮抗薬
Glutamate is the primary excitatory neurotransmitter in the brain, essential for neuronal communication. It plays a crucial role in synaptic transmission, ...
抗てんかん薬:SV2A タンパク質を介した神経伝達物質放出の調節剤
抗てんかん薬:SV2A タンパク質を介した神経伝達物質放出の調節剤
Antiepileptic drugs, like levetiracetam and brivaracetam, leverage the synaptic vesicle protein SV2A to mitigate seizures. SV2A is a transmembrane ...
抗てんかん薬:カリウムチャネル活性化剤
抗てんかん薬:カリウムチャネル活性化剤
The Antiepileptic drug ezogabine functions as a potassium channel activator by enhancing transmembrane potassium currents mediated by the KCNQ subtype of ...
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