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第9章

翻訳 RNAからタンパク質へ

翻訳
翻訳
Lesson: Translation Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following ...
tRNAの活性化
tRNAの活性化
Aminoacyl-tRNA synthetases are present in both eukaryotes and bacteria. Though eukaryotes have 20 different aminoacyl-tRNA synthetases to couple to 20 ...
リボソーム
リボソーム
Ribosomes translate genetic information encoded by messenger RNA (mRNA) into proteins. Both prokaryotic and eukaryotic cells have ribosomes. Cells that ...
並進精度の向上
並進精度の向上
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single ...
翻訳の開始
翻訳の開始
Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are ...
翻訳の終了
翻訳の終了
The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the ...
ナンセンス媒介性mRNA崩壊
ナンセンス媒介性mRNA崩壊
The Upf proteins that carry out nonsense-mediated decay (NMD) are found in all eukaryotic organisms, including humans. Each protein has an individual ...
分子シャペロンとタンパク質フォールディング
分子シャペロンとタンパク質フォールディング
The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form ...
プロテアソーム
プロテアソーム
Eukaryotic cells can degrade proteins through several pathways. One of the most important amongst these is the ubiquitin-proteasome pathway. It helps the ...
制御されたタンパク質分解
制御されたタンパク質分解
It is vital to regulate the activity of enzymatic as well as non-enzymatic proteins inside the cell. This can be achieved either through creating a ...
タンパク質:遺伝子から分解まで
タンパク質:遺伝子から分解まで
Within a biological system, the DNA encodes the RNA, and the nucleotide sequence in the RNA further defines the amino acid sequence in the protein. This ...
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