Applicazione e metodologia della tecnica NMR Non distruttivo ¹⁹F dominio del tempo per misurare il contenuto in prodotti contenenti fluoro di droga

0:51

Preparation of Samples and NMR Instrument for ¹⁹F TD-NMR Measurement

8:29

Conclusion

1:56

Measurement of the T₁ or Longitudinal Relaxation Time for Standard Pure API Samples

3:23

Measuring Calibration Samples with Pure API

4:29

Measuring Drug Product Samples as Tablets

6:59

Calculation of the Fluorinated API Drug Weight in the Formulated Drug Product Using the Calibration Curves

7:33

Results: Evaluation of the Average Drug Content of Cinacalcet in Tablet Dosage Forms by Low-field Fluorine-19 Time-domain Nuclear Magnetic Resonance

4:59

Generation of Calibration Curves with Pure API Samples and Adding the Data from Drug Product Samples as Tablets in the Calibration Curve