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Aditi Upadhye

Department of Microbiology,
Immunology,
Cancer Biology,
Department of Microbiology, Immunology, Cancer Biology

University of Virginia

BIOGRAPHY

Aditi Upadhye is a Postdoctoral Research Associate at the University of Virginia in the laboratory of Dr. Coleen

McNamara. She earned her B.Sc. in Biochemistry from Lyman Briggs College at Michigan State

University, where her coursework and exposure to translational research led her to pursue

graduate studies in biomedical sciences. Aditi received her PhD in December 2019 studying

B-1 cell-mediated protection against atherosclerosis in Dr. McNamara's lab. In the future, she plans to continue

pursuing research on immune mechanisms present in chronic inflammatory conditions and opportunities

to translate scientific discoveries to human health and disease.

PUBLICATIONS

Increased serum CXCL1 and CXCL5 are linked to obesity, hyperglycemia, and impaired islet function.

The Journal of endocrinology Aug, 2014 | Pubmed ID: 24928936

Regulation of Transcription Factors by Reactive Oxygen Species and Nitric Oxide in Vascular Physiology and Pathology.

Antioxidants & redox signaling 05, 2017 | Pubmed ID: 27841660

Perivascular Adipose Tissue Harbors Atheroprotective IgM-Producing B Cells.

Frontiers in physiology , 2017 | Pubmed ID: 28970806

c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells.

Cell reports 05, 2019 | Pubmed ID: 31116977

Cell- and Sex-Specific Role of FcγR (Fcγ Receptor) IIb in Experimental Atherosclerosis.

Arteriosclerosis, thrombosis, and vascular biology 07, 2019 | Pubmed ID: 31242029

Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked to Human Coronary Atherosclerosis.

Circulation research Oct, 2019 | Pubmed ID: 31549940

2019 Russell Ross Memorial Lecture in Vascular Biology: B Lymphocyte-Mediated Protective Immunity in Atherosclerosis.

Arteriosclerosis, thrombosis, and vascular biology 02, 2020 | Pubmed ID: 31852222

liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects.

Theranostics , 2020 | Pubmed ID: 31903139

INSTITUTIONS

University of Virginia

JOVE ARTICLES

Retroviral Overexpression of CXCR4 on Murine B-1a Cells and Adoptive Transfer for Targeted B-1a Cell Migration to the Bone Marrow and IgM Production

Aditi Upadhye¹,

Melissa Marshall²,

James C. Garmey²,

Timothy P. Bender³,

Coleen McNamara²

¹Department of Microbiology, Immunology, Cancer Biology, University of Virginia,

²Cardiovascular Research Center, University of Virginia,

³Beirne B. Carter Center for Immunology Research, University of Virginia

Immunology and Infection

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Aditi Upadhye

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Microbiology,Immunology,Cancer Biology,Department of Microbiology, Immunology, Cancer Biology

University of Virginia

Retroviral Overexpression of CXCR4 on Murine B-1a Cells and Adoptive Transfer for Targeted B-1a Cell Migration to the Bone Marrow and IgM Production

Department of Microbiology,
Immunology,
Cancer Biology,
Department of Microbiology, Immunology, Cancer Biology