Peptic Ulcer Disease (PUD) is characterized by the development of ulcers in the stomach or duodenal mucosa. Its pathophysiology is complex, involving a balance between damaging and protective elements.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
On the protective side:
The interplay of these factors either heightens acid-pepsin levels or weakens the mucosal barrier's resistance. Damaged mucosa struggles to produce sufficient mucus as a defense, leading to inflammation, harm, and mucosal erosion.
Aus Kapitel 10:
Now Playing
Gastric and Duodenal Disorders
306 Ansichten
Gastric and Duodenal Disorders
284 Ansichten
Gastric and Duodenal Disorders
264 Ansichten
Gastric and Duodenal Disorders
170 Ansichten
Gastric and Duodenal Disorders
141 Ansichten
Gastric and Duodenal Disorders
94 Ansichten
Gastric and Duodenal Disorders
74 Ansichten
Gastric and Duodenal Disorders
236 Ansichten
Copyright © 2025 MyJoVE Corporation. Alle Rechte vorbehalten