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Medical College of Fudan University

1 ARTICLES PUBLISHED IN JoVE

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Biochemistry

Determining Four Components in a Lipid Nanoparticle RNA Delivery System by Liquid Chromatography Combined with Evaporative Light Scattering Detector
Jia Zheng 1, Huijuan Jiang 1, Junqi Huang 2, Qiaoxia Liu 1, Hongyuan Hao 1
1Shimadzu (China) Co., Ltd., 2Medical College of Fudan University

Here, we establish a quantitative analysis method for four components in a lipid nanoparticle (LNP) RNA delivery system using high-performance liquid chromatography combined with an evaporative light scattering detector (ELSD). The method has good separation, high sensitivity, and high efficiency.

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