Evaluation of the In vivo Antitumor Activity of Polyanhydride IL-1α Nanoparticles
2.0K Views
•
09:57 min
•
June 28th, 2021
DOI :
June 28th, 2021
•M. M. Hasibuzzaman1,2, Kathleen A. Ross3,4, Aliasger K. Salem1,4,5,6, Balaji Narasimhan3,4, Andrean L. Simons1,2,3,5,6,7
1Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, 2Department of Pathology, University of Iowa, 3Department of Chemical and Biological Engineering, College of Engineering, Iowa State University, 4Nanovaccine Institute, Iowa State University, 5Division of Pharmaceutics and Translational Therapeutics, College of Pharmacy, University of Iowa, 6Holden Comprehensive Cancer Center, University of Iowa, 7Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa
Chapters in this video
0:04
Introduction
0:55
Preparation and Maintenance of HNSCC Cell Line
2:38
Tumor Implantation
3:14
Blood Collection and Serum Separation
4:20
Multiplexing of Collected Serum
4:51
Collection of Tumor and Inguinal Lymph Node and Preparation of Single-Cell Suspension
5:58
FACS Staining of Single-Cell Suspension
7:42
Results: IL-1α Antitumor Activity in HNSCC Mouse Model
9:03
Conclusion
Related Videos
14:10
Contrast Ultrasound Targeted Treatment of Gliomas in Mice via Drug-Bearing Nanoparticle Delivery and Microvascular Ablation
15.9K Views
14:20
Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
16.6K Views
08:03
Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
9.0K Views
07:59
A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines
8.8K Views
08:04
Evaluation of Nanoparticle Uptake in Tumors in Real Time Using Intravital Imaging
18.3K Views
14:04
Viral Nanoparticles for In vivo Tumor Imaging
17.2K Views
15:04
Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
12.1K Views
10:26
Using In Vitro Live-cell Imaging to Explore Chemotherapeutics Delivered by Lipid-based Nanoparticles
8.4K Views
07:33
Preparation, Characteristics, Toxicity, and Efficacy Evaluation of the Nasal Self-Assembled Nanoemulsion Tumor Vaccine In Vitro and In Vivo
1.6K Views
03:59
In Vivo Antitumor Efficacy Analysis of PDT: A Technique to Determine the Phototoxic Potential of a Photosensitizer in Tumor Bearing Mice
1.7K Views
Copyright © 2025 MyJoVE Corporation. All rights reserved