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Synaptic Microcircuit Modeling with 3D Cocultures of Astrocytes and Neurons from Human Pluripotent Stem Cells

12.2K Views

08:48 min

August 16th, 2018

DOI :

10.3791/58034-v

August 16th, 2018


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Synaptic Microcircuit

Chapters in this video

0:04

Title

0:49

Generation and Maintenance of Astrocyte Progenitors (hAstros) from hPSCs

2:41

Generation and Maintenance of Neurons (hNeurons) and Inducible Neurons (iNeurons) from hPSCs

3:27

Preparation and Maintenance of 3D Sphere Co-cultures

5:42

Measurement of Live Synaptic Physiology with Multielectrode Arrays (MEAs)

6:56

Results: Morphological and Physiological Characteristics of Synaptic Microcircuits

8:07

Conclusion

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