Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging
10.3K Views
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11:43 min
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December 30th, 2016
DOI :
December 30th, 2016
•Eugen Kubala*1,2,3, Kim A. Muñoz-Álvarez*1, Geoffrey Topping1, Christian Hundshammer1,2, Benedikt Feuerecker1, Pedro A. Gómez3,4, Giorgio Pariani1,5,6, Franz Schilling1, Steffen J. Glaser2, Rolf F. Schulte3, Marion I. Menzel3, Markus Schwaiger1
1Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, 2Department of Chemistry, Technische Universität München, 3GE Global Research, 4Zentralinstitut für Medizintechnik der Technischen Universität München (IMETUM), Technische Universität München, 5Institute for Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, 6IDG Institute of Developmental Genetics, Helmholtz Zentrum München
Chapters in this video
0:05
Title
1:11
Hyperpolarization of [1-13C]Pyruvate
3:47
Cell Culture Preparation
4:51
13C Magnetic Resonance Spectroscopy
6:10
13C Magnetic Resonance Imaging
9:20
Results: Metabolic Exchange of [1-13C]Pyruvate to [1-13C]Lactate in Prostate Carcinoma (PC3) Cells
10:40
Conclusion
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