The In Ovo Chick Chorioallantoic Membrane (CAM) Assay as an Efficient Xenograft Model of Hepatocellular Carcinoma
35.2K Views
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08:17 min
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October 9th, 2015
DOI :
October 9th, 2015
•Michael Li1,2, Ravi R. Pathak5, Esther Lopez-Rivera3, Scott L. Friedman1, Julio A. Aguirre-Ghiso4, Andrew G. Sikora5
1Department of Medicine, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, 2Department of Otolaryngology, Icahn School of Medicine at Mount Sinai, 3Division of Nephrology, Columbia University College of Physicians and Surgeons, 4Departments of Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, 5Bobby R. Alford Department of Otolaryngology - Head and Neck Surgery, Baylor College of Medicine
Chapters in this video
0:05
Title
1:44
Preparing the Egg for Inoculation: "Dropping" the CAM and Opening the Egg
3:57
Inoculation of the CAM with Tumor Cells
5:32
Harvesting Tumors from the CAM
6:24
Tumor Cell Dissociation
7:20
Results: The CAM Supports Growth of Three-Dimensional, Vascularized Tumors
7:44
Conclusion
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