JoVE Logo

Войдите в систему

Chapter 26

The Cytoskeleton II: Microtubules and Intermediate Filaments

Микротрубочки
Микротрубочки
Microtubules are the thickest cytoskeletal filaments with a diameter of 25 nm. In prokaryotic organisms, microtubules are commonly found in locomotory ...
Нестабильность микротрубочек
Нестабильность микротрубочек
Microtubules are hollow cylindrical filaments having a diameter of approximately 25 nm and a length that varies from 200 nm to 25 μm. GTP-bound ...
Образование микротрубочек
Образование микротрубочек
Microtubules are dynamic structures that undergo continuous assembly and disassembly. They originate from specialized multi-protein complexes known as ...
Белки, ассоциированные с микротрубочками (MAP)
Белки, ассоциированные с микротрубочками (MAP)
Microtubule function and architecture are regulated by an array of specialized proteins called microtubule-associated proteins or MAPs. These proteins are ...
Дестабилизация микротрубочек
Дестабилизация микротрубочек
The destabilization of microtubules can occur during different stages of the microtubule lifecycle, such as nucleation or elongation. It can take place at ...
Моторные белки, ассоциированные с микротрубочками
Моторные белки, ассоциированные с микротрубочками
Eukaryotic cells have different motor proteins for transporting various cargo within the cell. These motor proteins differ based on the filament they ...
Движение органелл и везикул
Движение органелл и везикул
In eukaryotic cells,  cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These ...
Сборка сложных структур микротрубочек
Сборка сложных структур микротрубочек
Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular ...
Микротрубочки в подвижности клеток
Микротрубочки в подвижности клеток
Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form ...
Механизм движения ресничек
Механизм движения ресничек
The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible ...
Микротрубочки в сигнализации
Микротрубочки в сигнализации
The primary cilium, made up of microtubules, acts as antennae on the cell surfaces for relaying external stimuli into the cells. These fine hair-like ...
Препараты, стабилизирующие микротрубочки
Препараты, стабилизирующие микротрубочки
Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the ...
Препараты, дестабилизирующие микротрубочки
Препараты, дестабилизирующие микротрубочки
Microtubules are dynamic structures and can be regulated by microtubule targeting agents (MTAs). Microtubule destabilizing drugs are a class of MTAs that ...
Структура промежуточных нитей
Структура промежуточных нитей
The intermediate filaments are one of three widely studied cytoskeletal filaments. They are so named as their diameter (10 nm) is in between that of ...
Типы промежуточных нитей накаливания
Типы промежуточных нитей накаливания
The intermediate filaments are an essential component of the cytoskeleton. Presently six types of intermediate filament have been identified. Type I and ...
Образование промежуточных нитей
Образование промежуточных нитей
Intermediate filaments are cytoskeletal proteins with higher tensile strength and flexibility than microfilaments and microtubules. Unlike the other two ...
Разборка промежуточных нитей накаливания
Разборка промежуточных нитей накаливания
Intermediate filaments (IFs) do not undergo spontaneous disassembly. Enzymes, kinases, and phosphatases add and remove phosphates from specific sites to ...
Септины
Септины
Septins are protein filaments forming the cytoskeleton along with the microtubules, microfilaments, intermediate filaments, and other accessory proteins. ...
Роль септинов
Роль септинов
Septins are the recently discovered fourth major protein component of the cytoskeleton, along with microfilaments, microtubules, and intermediate ...
JoVE Logo

Исследования

Образование

О JoVE

Авторские права © 2025 MyJoVE Corporation. Все права защищены