Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion
Please note that all translations are automatically generated. Click here for the English version.
3.0K Views
•
09:17 min
•
March 1st, 2022
DOI :
March 1st, 2022
•1Beijing Computational Science Research Center, 2Shenzhen JL Computational Science and Applied Research Institute, 3School of Medical Informatics and Engineering, Xuzhou Medical University, 4Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, 5Department of Physics and Astronomy, University of California, Irvine, 6Department of Chemistry, University of California, Irvine, 7NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine
Rozdziały w tym wideo
0:04
Introduction
0:45
Construction of the Markov State Model from Atomic Molecular Dynamics Simulations
6:26
Conducting Coarse-Grained Simulation to Sample Long-Time Dynamics
6:57
Results: Structure-Based Simulation and Sampling of Transcription Factor Protein Movements
8:45
Conclusion
Powiązane Filmy
12:54
Real-time Analysis of Transcription Factor Binding, Transcription, Translation, and Turnover to Display Global Events During Cellular Activation
13.4K Views
11:25
Enhanced Yeast One-hybrid Screens To Identify Transcription Factor Binding To Human DNA Sequences
7.8K Views
06:38
High Sensitivity Measurement of Transcription Factor-DNA Binding Affinities by Competitive Titration Using Fluorescence Microscopy
8.7K Views
09:58
Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis
2.7K Views
11:36
An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations
1.9K Views
07:05
Single-Molecule Imaging of EWS-FLI1 Condensates Assembling on DNA
2.3K Views
12:29
Identifying Transcription Factor Olig2 Genomic Binding Sites in Acutely Purified PDGFRα+ Cells by Low-cell Chromatin Immunoprecipitation Sequencing Analysis
9.2K Views
06:43
A Quantitative Assay to Study Protein:DNA Interactions, Discover Transcriptional Regulators of Gene Expression, and Identify Novel Anti-tumor Agents
18.5K Views
06:48
Single-Molecule Measurement of Protein Interaction Dynamics Within Biomolecular Condensates
3.2K Views
01:51
Test przesunięcia ruchliwości elektroforetycznej do wykrywania kompleksów czynnik transkrypcyjny-DNA
348 Views
Copyright © 2025 MyJoVE Corporation. Wszelkie prawa zastrzeżone